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Rare T Cells Fight Cancer
Jef Akst | May 1, 2017
A new approach to immunotherapy finds that the immune-cell clonotypes that come to the rescue start out at very low frequencies.
Neoantigens Enable Personalized Cancer Immunotherapy
Stephen P. Schoenberger and Ezra Cohen | Apr 1, 2017
Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.
Targeting Tregs Halts Cancer’s Immune Helpers
Ruth Williams | Apr 1, 2017
New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.
Infographic: Antibody Cancer Therapy
Ruth Williams | Mar 31, 2017
An experimental technique removes T cells that aid in vitro tumor growth.
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Neoantigens may serve as valuable targets for new immunotherapies.
HIV Vaccines May Help Tamp Down Virus
Kerry Grens | Feb 24, 2017
A fraction of HIV patients in a small, uncontrolled study were able to stop antiretroviral therapy after receiving the immune boosters.
More than 40 New Papers on Epigenetics Published
Jef Akst | Nov 22, 2016
The International Human Epigenome Consortium presents a series of studies on how epigenetics influences immunity, cell lineage determination, and differentiation.
Immune System Maintains Brain Health
Amanda B. Keener | Nov 1, 2016
Once thought only to attack neurons, immune cells turn out to be vital for central nervous system function.
One Antigen Receptor Induces Two T cell Types
Ruth Williams | Aug 26, 2016
Precursor T cells bearing the same antigen receptor adopt two different fates in mice.
Two NIH Labs Cease Reagent Production
Kerry Grens | Apr 20, 2016
Contamination concerns at cell therapy and radioactive tracer facilities spur production shutdowns.