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A computer-generated graphic showing a cross-section of red-colored bacteria, with the locations of the protein APOL3 labeled in green.
Human Protein Dissolves Bacterial Membranes
The protein, apolipoprotein L3, destroys invading microbes by acting as a detergent in the cytosol.
Human Protein Dissolves Bacterial Membranes
Human Protein Dissolves Bacterial Membranes

The protein, apolipoprotein L3, destroys invading microbes by acting as a detergent in the cytosol.

The protein, apolipoprotein L3, destroys invading microbes by acting as a detergent in the cytosol.

Tay-Sachs disease, cell & molecular biology
A bar of milk chocolate with the foil peeled back and a bite taken out
Q&A: Eating Milk Chocolate in the Morning Boosts Fat Metabolism
Amanda Heidt | Jun 30, 2021 | 6 min read
A study of 19 postmenopausal women found that eating a bar of chocolate in the morning affected their bodies differently than eating it at night, but neither led to weight gain.
A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?
a drawing of black goggles receiving a beam of light than is then transmitted to an eyeball. from the retina there is a zoom-in of blue and purple cells and purple viruses
Blind Patient Recovers Partial Vision with Optogenetics
Alejandra Manjarrez | May 24, 2021 | 4 min read
After receiving an intraocular injection of the gene for a light-sensitive protein, a 58-year-old man diagnosed with the neurodegenerative eye disease retinitis pigmentosa was able to locate objects on a table using engineered goggles.
a person in a white lab coat with a blue glove inserting a clear pcr tube into a which thermocycler while holding an orange box
Coronavirus Mutations Could Muddle COVID-19 PCR Tests
Jack J. Lee | May 17, 2021 | 4 min read
Researchers find that SARS-CoV-2 variants can evade primer-probe sets and recommend that diagnostic assays include multiple targets for reliability.
Close-up shot of smooth cauliflower polyps
Comprehensive Atlas of Reef-Building Coral’s Cells Created
Christie Wilcox | May 13, 2021 | 5 min read
Single-cell RNA sequencing helps to catalog the dozens of cell types present in a stony coral, including its elusive immune cells.
An underwater photo of the solitary tunicate Polycarpa mytiligera growing on a coral in the Red Sea
When Severed, This Solitary Tunicate Regrows as Three New Animals
Amanda Heidt | May 13, 2021 | 4 min read
While regeneration has long been the domain of colonial tunicates, a solitary species of sea squirt was able to regenerate into multiple, fully functional individuals within a month of being cut up.
screen shot from a microscopy video of a green cell exiting a red cell and then entering two other green cells in sequence as a yellow arrow follows the original green cell
Cancer Cells Parasitize Other Ones to Survive: Study
Marcus A. Banks | May 13, 2021 | 3 min read
Tumor cells missing a critical protein enter neighboring cells to sap their nutrients, then exit those hosts as intact cells, possibly primed to metastasize. Other scholars say it’s too early to know this for sure.
Can Single Cells Learn?
Catherine Offord | May 1, 2021 | 10+ min read
A controversial idea from the mid-20th century is attracting renewed attention from researchers developing theories for how cognition arises with or without a brain.
Aphid Salivary Gene May Regulate Gall Color
Asher Jones | May 1, 2021 | 2 min read
Whether the galls that aphids make on witch hazel leaves are red or green is associated with a gene expressed in the insects’ salivary glands.
Infographic: Investigating Whether Single Cells Learn
Catherine Offord | May 1, 2021 | 2 min read
Historical and modern experiments have hinted that unicelluar organisms can learn from their experiences, but the idea still has its critics.
Pink background with menstrual products off to the right
No Proof COVID-19 Vaccine Affects Menstruation or Fertility
Lisa Winter | Apr 27, 2021 | 2 min read
Following vaccination, some women claim their periods have changed, leading to rumors about how the shots affect recipients’ reproductive systems, and even others’ by proxy.  
obituary, obituaries, microbiology, molecular genetics, biochemistry, bioinformatics, Stanford University, University of Southern California, cell & molecular biology
Laurence “Larry” Kedes, Molecular Geneticist, Dies at 83
Amanda Heidt | Apr 26, 2021 | 4 min read
In addition to isolating the first protein-coding gene from a eukaryote, Kedes furthered scientists’ understanding of actin genes and also laid the foundations for modern DNA databases such as GenBank.
gamma delta t cell intestine gut mouse mice diet nutrient epithelial cell remodeling immune system
Mysterious Immune Cells Change the Gut Lining to Accommodate Diet
Annie Melchor | Apr 6, 2021 | 4 min read
A study shows gamma-delta T cells in mice respond to shifts in nutrients by changing the cellular composition of the intestinal epithelium.
Robert “Buzz” Baldwin, Early Expert in Protein Structures, Dies
Jef Akst | Apr 2, 2021 | 2 min read
Research by the Stanford University School of Medicine professor revealed how newly formed strings of amino acids fold into complex three-dimensional shapes.
High Stress Hormone Levels Halt Mouse Fur Growth
Jef Akst | Apr 1, 2021 | 4 min read
Corticosterone interferes with signaling in the skin that normally activates hair follicle stem cells, possibly explaining the link between stress and hair loss.
Cancer May Be Driven by DNA Outside of Chromosomes
Paul Mischel | Apr 1, 2021 | 10+ min read
In the last decade, researchers have come to realize that tumors harbor bits of extrachromosomal DNA that can drive malignancy.
Contributors
Asher Jones and Kerry Grens | Apr 1, 2021 | 3 min read
Meet some of the people featured in the April 2021 issue of The Scientist.
“Rogue” Protein Could Contribute to Humans’ High Cancer Rates
Asher Jones | Apr 1, 2021 | 2 min read
A mutant protein called Siglec-XII may promote carcinoma progression in humans, but inactivation of its gene seems to avoid the problem, according to a study.
Infographic: Steps in Cancer Metastasis
Shawna Williams | Apr 1, 2021 | 3 min read
It’s now thought that in many cases, cancer cells disseminate from the primary tumor site early on and lie dormant for long periods rather than only venturing out from primary tumors at an advanced stage.
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