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Scientists Continue to Use Outdated Methods
Catherine Offord | Jan 9, 2018
The use of underperforming computational tools is a major offender in science’s reproducibility crisis—and there’s growing momentum to avoid it.
3-D–Printed Ethoscopes Lower Barriers to Large-Scale Fly Behavior Studies
Ruth Williams | Jan 1, 2018
The DIY devices collect data and enable light stimulation, chamber agitation, and gas infusion.
Top Technical Advances in 2017
Shawna Williams | Dec 24, 2017
The year’s most impressive achievements include new methods to extend CRISPR editing, patch-clamp neurons hands-free, and analyze the contents of live cells.
CRISPR Proves Promising for Treating ALS in Mice
Katarina Zimmer | Dec 21, 2017
The gene-editing tool was effective in disabling a defective gene responsible for some forms of amyotrophic lateral sclerosis.
CRISPR Helps Mice Hear
Abby Olena | Dec 20, 2017
Researchers reduce the severity of hereditary deafness in mice with the delivery of CRISPR-Cas9 protein-RNA complexes that inactivate a mutant gene in their inner ears.
New Resource Ranks Chemical Probes for Human Proteins
Abby Olena | Dec 14, 2017
With many probes being seriously flawed, Probe Miner helps researchers find those that are most specific and effective for manipulating their chosen proteins.
Optical Cell Sorting
Rachel Berkowitz | Dec 1, 2017
Researchers are using light and new image processing tools for label-free cell characterization.
2017 Top 10 Innovations
Staff | Dec 1, 2017
From single-cell analysis to whole-genome sequencing, this year's best new products shine on many levels.
Infographic: Combo Method of Stem Cell Generation
Ruth Williams | Nov 30, 2017
Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.
The Next Generation of Noninvasive Brain Stimulation
Jef Akst | Nov 15, 2017
New techniques for activating or suppressing neural activity by zapping the skull’s surface allow researchers to target smaller and deeper areas of the brain.