ISTOCK, OONAL
Questions Raised About “Breakthrough” Therapies’ Clinical Support
Questions Raised About “Breakthrough” Therapies’ Clinical Support
Compared to other drugs, therapeutics given breakthrough status receive FDA approval on the basis of weaker trial evidence, a study finds.
Questions Raised About “Breakthrough” Therapies’ Clinical Support
Questions Raised About “Breakthrough” Therapies’ Clinical Support

Compared to other drugs, therapeutics given breakthrough status receive FDA approval on the basis of weaker trial evidence, a study finds.

Compared to other drugs, therapeutics given breakthrough status receive FDA approval on the basis of weaker trial evidence, a study finds.

techniques, disease & medicine
Bioethics Council: Gene-Editing Human Embryos Conditionally OK
Bioethics Council: Gene-Editing Human Embryos Conditionally OK
Shawna Williams | Jul 17, 2018
The UK-based organization encourages public debate about the issue but does not recommend immediate policy change.
Opinion: No, AI Will Not Replace Radiologists
Opinion: No, AI Will Not Replace Radiologists
Phil Shaffer | Jul 17, 2018
The adoption of machine-learning techniques to aid in diagnosis should be done with radiologists’ guidance.
Image of the Day: Eye-Opener
Image of the Day: Eye-Opener
Sukanya Charuchandra | Jul 17, 2018
An open-source microscopy method can super-resolve live cells even under low lighting.
CRISPR Gene Editing Deletes, Shuffles More Genes than IntendedCRISPR Gene Editing Deletes, Shuffles More Genes than Intended
CRISPR Gene Editing Deletes, Shuffles More Genes than Intended
Ashley Yeager | Jul 16, 2018
The DNA-cutting enzyme used in the technique is not as precisely targeted as scientists had thought, and investors take notice.
A Noninvasive Way to Control Individual Brain Regions
A Noninvasive Way to Control Individual Brain Regions
Catherine Offord | Jul 13, 2018
Researchers use a combination of ultrasound waves, genetic engineering, and synthetic drugs to switch specific neurons on and off in mice.
Higher Blood Pressure Has Links to Brain Lesions in Older Adults
Higher Blood Pressure Has Links to Brain Lesions in Older Adults
Sukanya Charuchandra | Jul 13, 2018
In a longitudinal study, researchers find that elderly people with higher pressure were more likely to show signs of Alzheimer’s disease in brain tissue.
Exosomes in Blood Indicate Mild TBI: Study
Exosomes in Blood Indicate Mild TBI: Study
Ashley Yeager | Jul 13, 2018
Levels of tau, amyloid-β 42, and IL-10 extracted from extracellular vesicles that started out in the brain were higher in military personal suffering head injuries compared with healthy soldiers.
Software-Based Chemical Screen Could Minimize Animal Testing
Software-Based Chemical Screen Could Minimize Animal Testing
Anna Azvolinsky | Jul 13, 2018
Researchers develop a machine-learning tool for toxicity analyses that is more consistent in predicting chemical hazards than assays on animals.
Electric Shock Allows for CRISPR Gene Editing Without a Viral Vector
Electric Shock Allows for CRISPR Gene Editing Without a Viral Vector
Ashley Yeager | Jul 12, 2018
Brief electroporation appears to make T cells more receptive to new genetic material, which could speed the development of immunotherapies.