Base Editors Cause Off-Target Mutations in RNA
Base Editors Cause Off-Target Mutations in RNA
A new study indicates that the modified CRISPR-Cas9 technology will need to be further refined before it can safely be used for research and therapeutic applications.
Base Editors Cause Off-Target Mutations in RNA
Base Editors Cause Off-Target Mutations in RNA

A new study indicates that the modified CRISPR-Cas9 technology will need to be further refined before it can safely be used for research and therapeutic applications.

A new study indicates that the modified CRISPR-Cas9 technology will need to be further refined before it can safely be used for research and therapeutic applications.

techniques, opinion, funding
Image of the Day: Multicolor Brain
Image of the Day: Multicolor Brain
Chia-Yi Hou | Apr 22, 2019
A newly developed imaging technology visualizes entire mouse brains in two and three dimensions using multicolor fluorescence microscopy.
Opinion: Transparency Is Critical to Defend Animal Research
Opinion: Transparency Is Critical to Defend Animal Research
Cindy Buckmaster | Apr 11, 2019
Research organizations should start sharing with the public information, stories, photos, and videos on how animals are cared for and used in science.
Brazil’s Researchers Criticize Budget Freeze
Brazil’s Researchers Criticize Budget Freeze
Catherine Offord | Apr 9, 2019
Scientists have attacked the government’s spending policies after it locked down nearly half of the money that had been allocated for science funding.
Image of the Day: Macrophages in Action
Image of the Day: Macrophages in Action
Chia-Yi Hou | Apr 5, 2019
Researchers watch cellular interactions in high definition as the immune cells absorb E. coli bacteria.
Bioethicists Concerned over Japan’s Chimera Embryo Regulations
Bioethicists Concerned over Japan’s Chimera Embryo Regulations
Katarina Zimmer | Apr 4, 2019
Many researchers see the move to relax the rules as a welcome change, yet some are worried the revisions don’t take public concerns enough into consideration.
Q&A: A 10,000-Genome Milestone for Shared Pediatric Cancer Data  
Q&A: A 10,000-Genome Milestone for Shared Pediatric Cancer Data  
Carolyn Wilke | Apr 1, 2019
Computational biologist Jinghui Zhang of St. Jude realized scientists could work more efficiently with tools and genomic data shared on the cloud.
Infographic: Functional Characterization of Microproteins
Infographic: Functional Characterization of Microproteins
Annie Rathore | Apr 1, 2019
Analyzing protein-protein interactions can shed light on what tiny proteins do in the cell.
Contending with Resistance in Cancer Immunotherapy
Contending with Resistance in Cancer Immunotherapy
Marissa Fessenden | Apr 1, 2019
Researchers describe ways to study how cancer cells evade therapies that harness the immune system.
The Dark Matter of the Human Proteome
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.