transcription factors, immunology, disease & medicine
Reprogrammed Cells Treat Diabetes in Mice
Reprogrammed Cells Treat Diabetes in Mice
Abby Olena | May 2, 2018
Researchers used a trio of transcription factors to transform pancreatic duct cells in vivo into β-like cells that secrete insulin and improve diabetes symptoms.
Diseases From Ticks and Mosquitoes Have Tripled
Diseases From Ticks and Mosquitoes Have Tripled
Kerry Grens | May 1, 2018
Warmer weather is thought to be behind the rise in vector-borne illnesses in recent years.
Researchers Succeed in Keeping Disembodied Pig Brains Alive
Researchers Succeed in Keeping Disembodied Pig Brains Alive
Catherine Offord | May 1, 2018
The organs showed neural activity for up to 36 hours, adding fuel to discussions about the ethics of future neuroscientific research.
Bullets and Ballots
Bullets and Ballots
Bob Grant | May 1, 2018
Researching the rare, but all-too-common, disease of gun violence in America will take a concerted political effort.
Colorblindness Study Reveals Unexpected Way to Make Blood Vessels
Colorblindness Study Reveals Unexpected Way to Make Blood Vessels
Ashley Yeager | May 1, 2018
Researchers stumbled across the connection while searching for ways to reduce vision problems in people with achromatopsia.
Preterm Labor May Be Sparked by Fetal Immune Reaction
Preterm Labor May Be Sparked by Fetal Immune Reaction
Ruth Williams | Apr 25, 2018
Immune cells targeting maternal antigens are abundant in the blood of premature infants, suggesting fetal intolerance of mom may instigate early labor.  
Image of the Day: Immune Cell In Action
Image of the Day: Immune Cell In Action
The Scientist Staff | Apr 23, 2018
By combining two new microscopy technologies, researchers filmed immune cells toiling away in the inner ear of a living zebrafish.
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Kerry Grens | Apr 16, 2018
Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  
Birth Defects Linked to Increased Risk of Childhood Cancer
Birth Defects Linked to Increased Risk of Childhood Cancer
Jim Daley | Apr 15, 2018
Certain non-chromosomal defects are strongly associated with specific childhood cancers.
New Ovarian Cancer Vaccine Shows Promise
New Ovarian Cancer Vaccine Shows Promise
Catherine Offord | Apr 12, 2018
A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.