translational science, immunology
A T-Cell Tweak Combats Advanced Breast Cancer
A T-Cell Tweak Combats Advanced Breast Cancer
Ashley Yeager | Jun 5, 2018
The immunotherapy eliminated a woman’s metastatic lesions and kept her disease-free for two years.
Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer
Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer
Sukanya Charuchandra | Jun 4, 2018
Merck’s Keytruda extended the lives of lung cancer patients by several months and appeared to stop the progression of advanced melanoma.  
Genetic Screen Predicts T-Cell Lymphoma Aggression
Genetic Screen Predicts T-Cell Lymphoma Aggression
Kerry Grens | May 9, 2018
Sequencing of a single gene can spot patients with a dangerous form of mycosis fungoides better than other prognostic tests.  
Preterm Labor May Be Sparked by Fetal Immune Reaction
Preterm Labor May Be Sparked by Fetal Immune Reaction
Ruth Williams | Apr 25, 2018
Immune cells targeting maternal antigens are abundant in the blood of premature infants, suggesting fetal intolerance of mom may instigate early labor.  
Image of the Day: Immune Cell In Action
Image of the Day: Immune Cell In Action
The Scientist Staff | Apr 23, 2018
By combining two new microscopy technologies, researchers filmed immune cells toiling away in the inner ear of a living zebrafish.
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Kerry Grens | Apr 16, 2018
Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  
New Ovarian Cancer Vaccine Shows Promise
New Ovarian Cancer Vaccine Shows Promise
Catherine Offord | Apr 12, 2018
A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.
Some Antibiotics Rev Up Host Immune Response to Viruses
Some Antibiotics Rev Up Host Immune Response to Viruses
Shawna Williams | Apr 9, 2018
The antimicrobial drug neomycin protects mice from some viral infections, complicating the picture of the relationship between antibiotics and susceptibility to viruses.
Opinion: We Have Been Naive About Naive T Cells
Opinion: We Have Been Naive About Naive T Cells
Jos├ę A.M. Borghans, Femke van Wijk, Theo van den Broek | Apr 6, 2018
Human naive T cells are far more heterogeneous than has long been appreciated, having implications for vaccine strategies.
Ruth Nussenzweig, Malaria Researcher, Dies
Ruth Nussenzweig, Malaria Researcher, Dies
Jim Daley | Apr 5, 2018
The microbiologist’s research led to the development of the first human malaria vaccine.