Adenovirus vectors deliver the genetic instructions for SARS-CoV-2 antigens directly into patients’ cells, provoking a robust immune response. But will pre-existing immunity from common colds take them down?

Take a break from the bench to puzzle and peruse.

A study of Nicaraguan children links prior Zika virus infection with aggravated dengue fever symptoms.

Some researchers express skepticism given the lack of data about the vaccine’s safety and efficacy, and the country plans to vaccinate healthcare workers, teachers, and others even before testing is complete.

Screens of hundreds of drug excipients reveal that some can interact with biological targets, contradicting their FDA categorization as inert.

How llamas and superglue might lead to antiviral therapies

The medical scientist made important contributions to polio treatment and Australian environmental policy—despite substantial resistance.

Vaccine experts divided on whether that level of protection is too low or too demanding.

Accounting for a limited stockpile of cholera vaccine can provide insight into the most effective way to distribute future COVID-19 vaccines.