vaccine, genetics & genomics, cancer
Mitochondrial DNA Plays a Role in Metastasis
Mitochondrial DNA Plays a Role in Metastasis
Kerry Grens | Apr 18, 2018
Experiments in mice show that mitochondria, both within the tumor and beyond, can make the difference between promoting or inhibiting cancer spread.
How Kidney Cancer Evolves
How Kidney Cancer Evolves
Jim Daley | Apr 18, 2018
Renal cell carcinoma tumors have three different evolutionary fates, each associated with specific clinical outcomes.
Immune Therapy Improves Lung Cancer Patients’ Survival
Immune Therapy Improves Lung Cancer Patients’ Survival
Jim Daley | Apr 17, 2018
Pembrolizumab combined with chemotherapy nearly doubles survival rates and shrinks tumors in some individuals.
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Kerry Grens | Apr 16, 2018
Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  
Birth Defects Linked to Increased Risk of Childhood Cancer
Birth Defects Linked to Increased Risk of Childhood Cancer
Jim Daley | Apr 15, 2018
Certain non-chromosomal defects are strongly associated with specific childhood cancers.
Estonia Offers Free Genetic Testing to Residents
Estonia Offers Free Genetic Testing to Residents
Diana Kwon | Apr 13, 2018
The nationwide experiment will initially include around 100,000 volunteers.
New Ovarian Cancer Vaccine Shows Promise
New Ovarian Cancer Vaccine Shows Promise
Catherine Offord | Apr 12, 2018
A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.
Wound-Healing in Mice Triggers Growth of Dormant Tumors
Wound-Healing in Mice Triggers Growth of Dormant Tumors
Jim Daley | Apr 12, 2018
Treating mice with anti-inflammatory drugs following surgery reduced the size of tumors.
Sweet Tooth Gene Tied to Less Body Fat
Sweet Tooth Gene Tied to Less Body Fat
Kerry Grens | Apr 11, 2018
A study of more than 450,000 people finds a certain genetic variant associated with eating more carbs is linked to a thicker waist and higher blood pressure, but less fat.  
Image of the Day: Tumor Organoids
Image of the Day: Tumor Organoids
The Scientist Staff | Apr 11, 2018
Miniature versions of bladder cancers could help physicians identify personalized treatment options for patients.