vaccine, immunology
Targeting Tregs Halts Cancer’s Immune Helpers
Targeting Tregs Halts Cancer’s Immune Helpers
Ruth Williams | Apr 1, 2017
New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.
Infographic: Targeting Cancer Antigens
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Neoantigens may serve as valuable targets for new immunotherapies.
Infographic: Antibody Cancer Therapy
Infographic: Antibody Cancer Therapy
Ruth Williams | Mar 31, 2017
An experimental technique removes T cells that aid in vitro tumor growth.
Anti-Flavivirus Antibodies Enhance Zika Infection in Mice
Anti-Flavivirus Antibodies Enhance Zika Infection in Mice
Anna Azvolinsky | Mar 30, 2017
Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.
Experimental MERS Treatments Target Host Cell Receptor
Experimental MERS Treatments Target Host Cell Receptor
Ashley Yeager | Mar 30, 2017
Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.
Pathway to Polio Virulence Revealed
Pathway to Polio Virulence Revealed
Ashley P. Taylor | Mar 23, 2017
Using epidemiological and laboratory data, scientists have mapped out a sequence of mutations through which the attenuated oral polio vaccine reverts to a virulent virus.
HIV Vaccines May Help Tamp Down Virus
HIV Vaccines May Help Tamp Down Virus
Kerry Grens | Feb 24, 2017
A fraction of HIV patients in a small, uncontrolled study were able to stop antiretroviral therapy after receiving the immune boosters.
RNA Vaccine for Zika Shows Promise
RNA Vaccine for Zika Shows Promise
Amanda B. Keener | Feb 2, 2017
Researchers use modified messenger RNA to produce a vaccine that protected mice and nonhuman primates from infection.
Unique Antibodies Open Path Toward New HIV Vaccines
Unique Antibodies Open Path Toward New HIV Vaccines
Amanda B. Keener | Jan 27, 2017
A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and treatments that target multiple strains of the virus.
Toward Breaking the Cold Chain
Toward Breaking the Cold Chain
Kerry Grens | Jan 24, 2017
Research efforts aim to obviate the need for vaccine refrigeration.