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DNA-Based Zika Vaccine Reaches Phase 2
Tracy Vence | Apr 4, 2017
An NIAID-sponsored clinical trial advances beyond safety testing.
Making CAR T-Cell Therapy Safer
Catherine Offord | Apr 1, 2017
Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.
Gel Scaffolds for Delivery of Immunotherapies
Rachel Berkowitz | Apr 1, 2017
Using biocompatible polymers to carry cancer immune therapies directly to the tumor
Neoantigens Enable Personalized Cancer Immunotherapy
Stephen P. Schoenberger and Ezra Cohen | Apr 1, 2017
Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.
Targeting Tregs Halts Cancer’s Immune Helpers
Ruth Williams | Apr 1, 2017
New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.
Infographic: Antibody Cancer Therapy
Ruth Williams | Mar 31, 2017
An experimental technique removes T cells that aid in vitro tumor growth.
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Neoantigens may serve as valuable targets for new immunotherapies.
Anti-Flavivirus Antibodies Enhance Zika Infection in Mice
Anna Azvolinsky | Mar 30, 2017
Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.
Experimental MERS Treatments Target Host Cell Receptor
Ashley Yeager | Mar 30, 2017
Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.
Pathway to Polio Virulence Revealed
Ashley P. Taylor | Mar 23, 2017
Using epidemiological and laboratory data, scientists have mapped out a sequence of mutations through which the attenuated oral polio vaccine reverts to a virulent virus.