Identifying molecular targets for SARS-CoV-2 therapeutics.

Genetic analyses suggest that the virus came from a patient who survived the 2013–2016 West African outbreak.

Sabra Klein, a biologist at Johns Hopkins Bloomberg School of Public Health, describes how SARS-CoV-2 affects men and women differently.

Sam Wilson discusses a user-friendly set of resources that he and his collaborators developed to aid labs pivoting to study COVID-19.

The P.1 variant, which has also been detected in five US states, could be responsible for cases of reinfection, according to a preprint.

Stronger interferon production, greater T cell activation, and increased susceptibility to autoimmunity are just some of the ways that females seem to differ from males.

B.1.525 shares a mutation with the B.1.351 variant first detected in South Africa that seems to allow the virus to dodge the immune system.

Researchers identify deletions in the N-terminal domain of the spike protein that allow the coronavirus to avoid antibody neutralization and that may contribute to the emergence of new variants.

An investigation by the World Health Organization into the origins of COVID-19 will instead focus on the virus’s animal origins and the possibility of spread through frozen foods.