Courtesy of Leica Microsystems
Confocal and multiphoton microscopes are standard fare in academic imaging facilities, but ultrahigh-resolution systems generally have a smaller user base – namely, their inventors. Soon facilities around the world can have a piece of the pie – 4Pi, that is.
Unlike a conventional microscope that views a sample from above or below using one objective, the 4Pi microscope uses two opposing objectives to view the sample from both sides. The combined light creates a sharp spot that increases resolution in the Z direction.
The TCS 4Pi microscope offers a four- to seven-fold improvement in axial resolution over standard confocal and...