Distinguishing Th1 and Th2 Cells

Reagents That Distinguish Th1 and Th2 cells Courtesy of R&D SystemsSchematic representation of cytokines influencing the development of antigen-activated naive CD4+ T cells into Th1 and Th2 cells. Editor's note: Although individual techniques are associated with specific researchers in this article, it should be noted that these investigators commonly use several different techniques to analyze T lymphocyte populations. The human body is constantly under siege. It must defend itself fr

Jeffrey Perkel
May 13, 2001

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Courtesy of R&D Systems

Schematic representation of cytokines influencing the development of antigen-activated naive CD4+ T cells into Th1 and Th2 cells.



Editor's note: Although individual techniques are associated with specific researchers in this article, it should be noted that these investigators commonly use several different techniques to analyze T lymphocyte populations.

The human body is constantly under siege. It must defend itself from a whole host of bacterial, parasitic, and viral invaders, not to mention rogue cancerous cells. The immune system is the primary line of defense in this game of chess, recognizing and ignoring "self" antigens, while vigorously attacking foreign ones. T lymphocytes, the strategists in this game, both direct the responses of the rest of the immune system and play an active role in it. T cells orchestrate the immune response via the production of cytokines--secreted proteins that instruct...