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Science in a New Light

Microscopy Image Analysis Software Actin (red), mitochrondria (green), and nucleus (blue) signals merged by Scanalytics' IPLab Software The science of microscopy, especially how microscopic observations are made and data are collected and displayed, has come a long way since the days of Carl Zeiss. The last decade has seen a resurgence in the use of optical microscopy in basic research, due in part to advances in instrumentation. Confocal technology, high resolution solid state cameras such as

Carol Wright-smith

Microscopy Image Analysis Software


Actin (red), mitochrondria (green), and nucleus (blue) signals merged by Scanalytics' IPLab Software
The science of microscopy, especially how microscopic observations are made and data are collected and displayed, has come a long way since the days of Carl Zeiss. The last decade has seen a resurgence in the use of optical microscopy in basic research, due in part to advances in instrumentation. Confocal technology, high resolution solid state cameras such as the slow scan, cooled charge coupled device (CCD) camera, and new probes for small molecules are contributing to this trend.

For many years the still-film camera attached to a microscope was the method of choice for image capture. Although used by many researchers today, the still-film camera is slowly being replaced by video-digital imaging systems. These new imaging systems offer unprecedented opportunities to study the full gamut of cellular structure and physiology. They...

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