Sugars And Splice: Glycobiology: The Next Frontier

Table of Carbohydrate Products Model of glycoprotein supplied by Seikagaku America Glycobiology. It has been called the "last frontier of pharmaceutical discovery." Hampered by a lack of economical and convenient tools, however, advances in glycobiology have been largely overshadowed by the rush to exploit PCR and the ready availability and comparative simplicity of the tools and enzymes for molecular biology. But that is changing. By all reports, the field of glycoprotein and carbo

Michael Brush
Jul 18, 1999
Table of Carbohydrate Products


Model of glycoprotein supplied by Seikagaku America


Glycobiology. It has been called the "last frontier of pharmaceutical discovery." Hampered by a lack of economical and convenient tools, however, advances in glycobiology have been largely overshadowed by the rush to exploit PCR and the ready availability and comparative simplicity of the tools and enzymes for molecular biology. But that is changing.

By all reports, the field of glycoprotein and carbohydrate analysis and synthesis is making a comeback and has a bright future. Fueled by recent Food and Drug Administration requirements for the characterization of the oligosaccharide portions of recombinant proteins with pharmaceutical applications, new findings concerning the roles carbohydrates play in biological systems, and the rise of proteomics, industry insiders report much optimism about the growth of the carbohydrate analysis market.

The field of glycobiology has recently seen plenty of shuffling among the companies that manufacture and...