Toxico-Logic
Graphic: Cathleen Heard Because most drugs undergo development and approval for seven to 10 years before coming to market, researchers are always looking for ways to speed the process. Preclinical drug testing involves both in vitro and animal assays that assess efficacy and potential side effects to predict how the agent will affect humans. Drug toxicity can result in such things as cancer and birth defects, so government agencies have set forth strict guidelines for toxicological testing. In p
Jan 9, 2000
Graphic: Cathleen Heard |
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In Vitro Toxicological Models
A drug can be toxic at different levels, but drug-induced mutagenesis of DNA underlies many adverse effects. Genotoxicity tests measure a...
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