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Cell Culture In A Chip

Bellco Glass, Inc., has recently been licensed to manufacture and distribute the newly patented GenesisChip. The GenesisChip is the latest creation of Mark Lyles, winner of the Mind Science Award for his invention of ceramic polymer dental fillings. Lyles's latest venture is the application of glass and ceramic polymers to cell culture scaffolds. His patented PRIMM (Polymer Rigid Inorganic Matrix Material) resolves one of the important problems that interferes with cell growth in plastic scaffo

Brent Johnson

Bellco Glass, Inc., has recently been licensed to manufacture and distribute the newly patented GenesisChip. The GenesisChip is the latest creation of Mark Lyles, winner of the Mind Science Award for his invention of ceramic polymer dental fillings. Lyles's latest venture is the application of glass and ceramic polymers to cell culture scaffolds. His patented PRIMM (Polymer Rigid Inorganic Matrix Material) resolves one of the important problems that interferes with cell growth in plastic scaffolds.


The Bellco GenesisChip
As Lyles explains, plastics are hydrophobic and must be pretreated to have a charged hydrophilic surface. Glass, however, is an amorphous silica that forms tetrahedral bonds capable of having a high negative charge. This negative charge holds water to the surface of the chip, keeping the scaffold as well as the tissue culture hydrated. In addition to its negative polarity, the polymer material is also very strong and highly porous. In fact,...

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