For Life Scientists Date: March 4, 1996
(The Scientist, Vol:10, #5, pg.17 & 19, March 4, 1996)
(Copyright ©, The Scientist, Inc.)
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When two or more different biomolecules are present in a solution and a researcher wishes to study only one, the technique considered most often to achieve the separation is chromatography. Biochromatography in its various guises has been driven in part by the biopharmaceutical industry's demand for better and faster protein- purification technologies. It has evolved into a fully automated, computer-controlled process suitable for separating small amounts of material on the research scale, as well as to achieve process-scale quantities of therapeutic biochemicals.
Life scientists use chromatography techniques to purify proteins or to separate nucleic acids as commonly as chemists use them to analyze organic and inorganic compounds. "As a science, chromatography has its roots in chemistry, where it has long been used to...