Packard CytoGem localization of cellular peroxisomes and nuclei.
One of the latest developments of GFP technology is found in Packard Instrument Company's collection of organelle-targeted sapphire-blue CytoGems. Different organelle targeting signals have been subcloned in pGFPsph-N or pGFPsph-C vectors. These organelle-targeting sequences guide the sapphire-blue protein to a single organelle in mammalian cells; the six possible cell-targeting sites are mitochondria, nucleus, peroxysome, cytoplasm, plasma membrane, and endoplasmic reticulum.
Erik Joly, group leader at BioSignal Inc. (Montreal, Quebec), thinks the organelle-targeting vectors will be a welcome sight for researchers performing subcellular colocalization studies (Biosignal...
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