Magnetize Your Separations

Particles from PerSeptive Biosystems PerSeptive Biosystems' BioMag® product line includes streptavidin-coupled superparamagnetic particles that can be used to capture biotinylated compounds. The company has recently developed a more efficient method for coupling streptavidin to the BioMag® particles. The resultant BioMag® Streptavidin Ultra-Load Particle has more attached streptavidin, and therefore a greater biotin-binding capacity, than did previous versions of the product. The im

Deoborah Wilkinson
Sep 13, 1998

Particles from PerSeptive Biosystems

PerSeptive Biosystems' BioMag® product line includes streptavidin-coupled superparamagnetic particles that can be used to capture biotinylated compounds. The company has recently developed a more efficient method for coupling streptavidin to the BioMag® particles. The resultant BioMag® Streptavidin Ultra-Load Particle has more attached streptavidin, and therefore a greater biotin-binding capacity, than did previous versions of the product. The improved particle has been on the market since February of this year, when it replaced the older version.

Both the formerly and currently offered streptavidin-conjugated particles are based on BioMag® particles. These particles are approximately 1µm in diameter and differ from some of the other commercially available chromatography beads in that they are irregularly shaped. The surface areas of these non-uniform particles are 20-30 times greater than those of spherical, uniform particles of the same diameter. Harry Glorikian, a product manager at PerSeptive Biosystems, explains...

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