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New Disrupters Help Cell Biologists Retrieve Products

Many experiments in cell biology require researchers to break open cells and then retrieve their contents. For example, the production of recombinant proteins in biotechnology relies on cell and tissue cultures--and cell disruption is essential to retrieving sought-after cell products. The technology used must be powerful enough to disrupt cell membranes and, possibly, cell walls, yet gentle enough so that the organelles and macromolecules inside the cells are not smashed, shattered, or boiled

Ricki Lewis
Many experiments in cell biology require researchers to break open cells and then retrieve their contents. For example, the production of recombinant proteins in biotechnology relies on cell and tissue cultures--and cell disruption is essential to retrieving sought-after cell products. The technology used must be powerful enough to disrupt cell membranes and, possibly, cell walls, yet gentle enough so that the organelles and macromolecules inside the cells are not smashed, shattered, or boiled away.

scale cell-disruption technologies.

BioSpec Products Inc.
P.O. Box 722
Bartlesville, Okla. 74005
Phone/Fax: (918) 336-3363
Products: Mini Beadbeater, $988; Biohomogenizer (rotor-stator),
$485

Cole-Parmer Instrument Co.
7425 North Oak Park Ave.
Chicago, Ill. 60648
(708) 647-7600
Fax: (708) 647-9660 Products: 50-watt ultrasonic processor, $1,495; shaking bead mill, $485-530; rotor-stator generators, $500-$690

Glas-Col Apparatus Co.
711 Hulman St.
Terre Haute, Ind. 47802
(812) 235-6167
Fax: (812) 234-6975
Product: BioNeb Cell Disruption System, $3,965-$4,065, depending on capacity...

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