Out-of-the-Box Proteomics Analysis

Proteomics may be the hot buzzword in biology, but proteomics researchers still lack the integrated, "off-the-shelf" tools that have come to characterize genomic research. Now, however, San Jose, Calif.-based Thermo Finnigan offers these scientists an all-in-one package with its recently released ProteomeX™ Workstation, a complete proteomics system. The ProteomeX Workstation is a multidimensional liquid chromatography/mass spectrometry (LC/MS) package that combines three successful Thermo

Paul Thacker
May 12, 2002
Proteomics may be the hot buzzword in biology, but proteomics researchers still lack the integrated, "off-the-shelf" tools that have come to characterize genomic research. Now, however, San Jose, Calif.-based Thermo Finnigan offers these scientists an all-in-one package with its recently released ProteomeX™ Workstation, a complete proteomics system.

The ProteomeX Workstation is a multidimensional liquid chromatography/mass spectrometry (LC/MS) package that combines three successful Thermo Finnigan components: an LCQ™ Deca XP ion trap mass spectrometer, Surveyor® HPLC, and new BioWorks™ 3.0 software, including TurboSEQUEST®. "This is one-stop shopping for proteomics," says Ken Miller, product marketing manager for proteomics.

The ProteomeX's multidimensional LC/MS allows a researcher to analyze proteins in complex samples, such as bacteria, plasma, or a human cell line. After protease digestion, the peptides in the sample are separated by capillary cation exchange followed by high-resolution reversed-phase LC. The mass spectrometer then detects and sequences the separated peptides. Finally, protein...