Run, Don't Walk
System speeds up the pace of sequencing Schematic of New England Biolab's Genome Priming System Transposons are nothing new to molecular biologists--they have been used since the early 1970s for creating mutations, as well as for moving sequences from place to place in vivo. In the Genome Priming System (GPS™), New England BioLabs (NEB) has developed a novel, in vitro application of transposons for the production of sequencing templates. GPS replaces primer walking, nested deletions, an
Feb 14, 1999
System speeds up the pace of sequencing
![]() Schematic of New England Biolab's Genome Priming System |
Transposition can be a complicated process, requiring as many as four proteins and often resulting in complex products. But recently, Nancy Craig and Anne Stellwagen1,2 from Johns Hopkins University isolated a mutant that will transpose in vitro through a simple procedure to yield simple products. NEB's...
Interested in reading more?
Become a Member of
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member?