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IGEN's ORIGEN Analyzer For diagnostics, drug discovery, and basic research, nothing beats the right assay. IGEN International of Gaithersburg, Md., has developed a new electrochemiluminescence (ECL) detection process, termed ORIGEN Technology, that can be applied to many different types of binding assays. IGEN's M-SERIES Analyzer uses ECL to speed immunoassays, quantitation of nucleic acids, receptor-ligand binding assays, and measurement of viruses and bacteria. IGEN's ORIGEN Technology

Bob Sinclair


IGEN's ORIGEN Analyzer
For diagnostics, drug discovery, and basic research, nothing beats the right assay. IGEN International of Gaithersburg, Md., has developed a new electrochemiluminescence (ECL) detection process, termed ORIGEN Technology, that can be applied to many different types of binding assays. IGEN's M-SERIES Analyzer uses ECL to speed immunoassays, quantitation of nucleic acids, receptor-ligand binding assays, and measurement of viruses and bacteria.

IGEN's ORIGEN Technology is based upon the measurement of light generated by the oxidation and reduction of a ruthenium metal ion at the surface of an electrode. The ruthenium chelate is only brought to the electrode when the binding interaction under study occurs, so a measurement of emitted light precisely quantitates specific binding.

The M-SERIES Analyzer is a flexible instrument that accommodates sandwich, direct, and competitive assay designs. A sandwich-type ORIGEN immunoassay, for example, requires several components: A sample containing the analyte under study, an analyte-recognizing antibody...

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