New Screening Approach Reveals Novel Regulators of Microcephaly
New Screening Approach Reveals Novel Regulators of Microcephaly
Researchers combine organoids, CRISPR-Cas9, and cellular barcoding technologies to identify genes that influence brain size.
New Screening Approach Reveals Novel Regulators of Microcephaly
New Screening Approach Reveals Novel Regulators of Microcephaly

Researchers combine organoids, CRISPR-Cas9, and cellular barcoding technologies to identify genes that influence brain size.

Researchers combine organoids, CRISPR-Cas9, and cellular barcoding technologies to identify genes that influence brain size.

The Literature
How RNAs Called SINEUPs Upregulate Translation
How RNAs Called SINEUPs Upregulate Translation
Catherine Offord | Jan 1, 2021
The recently discovered long noncoding RNAs seem to boost the production of specific proteins in the cell by interacting with RNA-binding proteins, researchers find.
Stress-Induced Chromosome Changes Protect Flies’ Aging Brains
Stress-Induced Chromosome Changes Protect Flies’ Aging Brains
Lisa Winter | Dec 1, 2020
Brain cells in older Drosophila tend to have more than two complete sets of chromosomes, and that polyploidy most likely has a protective function, a study shows.
Immune Genes Protect Cells from Ebola Virus and SARS-CoV-2
Immune Genes Protect Cells from Ebola Virus and SARS-CoV-2
Rachael Moeller Gorman | Dec 1, 2020
A pathway involved in the adaptive immune system, a relative newcomer in the world of pathogen defense, may have a more ancient role in protecting cells from invading viruses.
Unearthed: World’s Oldest Animal Sperm—And It’s Giant
Unearthed: World’s Oldest Animal Sperm—And It’s Giant
Max Kozlov | Dec 1, 2020
The sperm, belonging to a tiny marine crustacean, dates back nearly 100 million years, making it the most ancient animal sperm found to date.
Herbivore Body Size Influences Grazing Behavior, Poop Quality
Herbivore Body Size Influences Grazing Behavior, Poop Quality
Catherine Offord | Nov 1, 2020
Researchers disentangle complex connections among vegetation, herbivores, and dung in the South African savanna.
Tropical Birds Differ in Their Responses to Drought
Tropical Birds Differ in Their Responses to Drought
Shawna Williams | Nov 1, 2020
Long-lived species decrease their reproduction more than short-lived species in response to lower-than-normal precipitation, and thereby gain a survival advantage, a study finds.
How a Centipede Survives its Own Species’ Venom
How a Centipede Survives its Own Species’ Venom
Shawna Williams | Nov 1, 2020
The same toxin targets different receptors in prey and conspecifics to deliver either a lethal or non-lethal blow.
Neural Connections Bolstered in Monkeys That Lift Weights
Neural Connections Bolstered in Monkeys That Lift Weights
Jef Akst | Oct 1, 2020
A study in two macaques reveals the importance of increasing connectivity between muscles and the reticulospinal tract that runs from the brain stem down the spinal cord.
Non-Concussive Head Hits Influence the Brain’s Microstructure
Non-Concussive Head Hits Influence the Brain’s Microstructure
Lisa Winter | Oct 1, 2020
Comparing the brain scans of high-impact rugby players with those of athletes in noncontact sports, such as rowing and swimming, revealed tiny, yet significant, differences in the brain’s white matter.