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M. Hatori et al., “Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet,” Cell Metab, 15:848-60, 2012.
Circadian disruptions can prime animals toward obesity, but does the maintenance of diurnal eating rhythms prevent excess weight gain? Satchidananda Panda at the Salk Institute and his colleagues found that mice fed a high-fat diet only during normal waking hours staved off obesity, metabolic dysfunction, and liver damage—all of which plagued animals with access to food around the clock.
Both groups ate the same number of calories, but after 18 weeks, the free-feeding mice weighed about 45 grams, compared to about 33 grams...