Sourcing high-quality proteins with batch-to-batch consistency can be a challenge, as endotoxin levels and/or non-native protein conformations and post-translational modifications can affect safety and performance.
Abcam’s new premium-grade proteins are manufactured in mammalian cell lines under animal-free conditions limiting endotoxins to ultra-low levels (< 5 EU/mg). The use of mammalian cell lines produces proteins with the desired conformation and correct post-translational modifications for optimal bioactivity. They resemble the proteins’ native state, helping to ensure a safe and consistent outcome during drug discovery, development and manufacturing.
Developed by a team of industry-expert protein scientists, each batch is validated using state-of-the-art technology to ensure consistent quality regarding integrity, purity, concentration, mono-dispersity and correct folding.
Abcam can also design, manufacture and validate proteins to custom needs and specifications. As a supplier of proteins for a broad range of applications, Abcam provides a comprehensive range of bioactive and research-grade proteins that enable additional cost-effective quality solutions.
Abcam’s premium-grade bioactive proteins provide:
Ultra-low endotoxin levels, < 5 EU/mg
Native post-translational modifications
> 95% purity
Manufactured under ISO9001
Batch-to-batch consistency monitored by sophisticated quality control, addressing identity, integrity, purity, concentration, folding and aggregation using methods such as LCMS, light scattering and thermal denaturation
Premium protein product certificate of analysis provided