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BRIEF

Clarifying and Filtering Cells for Protein Purification

Cell filtration in a 24-well plate.

PALL-Laboratory

 

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Scientists largely use centrifugation and filtration to clarify complex cell cultures when recovering extracellular proteins, such as monoclonal antibodies (mAbs). However, these steps can be time-consuming and costly for labs growing their cultures in 24-well plates. Furthermore, this manual process produces significant variability.

Download this scientific brief from Pall Laboratory to learn about

  • An alternative to using centrifugation/filtration/flocculation to clarify and sterilize mammalian cell cultures
  • New 24-well clarification and sterile filtration plates, and a 24-well sterilization-only filter plate for recovering proteins present in supernatant