During the Society of Toxicology Meeting from 11-15 March 2018 at the Henry B. González Convention Center in San Antonio, TX (USA), Lonza will present two posters highlighting its latest research into developing more physiologically relevant in vitro cell-culture models for ADME-Tox testing. Lonza is also sponsoring two symposia at the meeting featuring the use of cell-culture models that better mimic the in vivo environment for enhanced research into drug-induced liver injury and hepatic signaling pathways and for improved in vitro hepatotoxicity testing. Poster Presentation: Comparison of Hepatocytes in Monolayer and RAFT™ 3D Cell Culture System
With studies suggesting primary hepatocytes can quickly lose many of their in vivo functions when cultured as a monolayer – the most commonly used approach for drug metabolism and toxicity experiments – researchers need more reliable in vitro liver models. To address this need, on Monday, 12 March, from 10:45 am–12:15 pm...
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