Loop Genomics Launches Most Accurate SARS-CoV-2 Long-read Sequencing for Research Use

Loop Genomics’ sequencing technology generates viral amplicon long-reads with only 1/25,000 errors per bp

Loop Genomics
Apr 23, 2020

Loop Genomics has launched a new service for long-read sequencing of long amplicons of SARS-CoV-2, the virus that causes COVID-19 disease, leveraging their ability to generate long-amplicon sequencing reads using Illumina sequencers and delivering long-read data with error rates that enable strain and quasi-species resolution.   

“SARS-CoV-2 has a 30kb long genome, which is at the very high end of genome size for RNA viruses. Characterizing the significance of different strains and quasi-species with mutations thousands of base pairs apart requires ultra-high fidelity long-reads and is therefore often overlooked due to the limitations of short read sequencing. Loop Genomics’ ultra-low error rate long-reads provides the viral genome sequencing resolution needed to better understand SARS-CoV-2 biology and facilitate epidemiology as well as drug and vaccine development efforts”.  says Tuval Ben Yehezkel PhD, CEO and founder of Loop Genomics. 

Loop’s service lab leverages existing Illumina short-read infrastructure and its software to generate SARS CoV-2 synthetic long-reads. Additionally, hospitals, public health and reference laboratories can use Loop’s Long PCR Amplicon kit with Illumina sequencers they already have in their lab or core facility to generate SARS CoV-2 long reads.  

“We want researchers to gain valuable insight that only accurate long-read viral sequencing data can provide them.  We are in a unique position to assist critical research at this time with our technology and are very excited to do so.”, says Tuval Ben Yehezkel PhD, CEO and founder of Loop Genomics.