SP Scientific announces the introduction of the LyoModelling Calculator (LMC) - a powerful new software utility that enables those developing freeze drying cycles to calculate the time required for primary drying and the maximum product temperature based on user data input.
This free software resource is available on the SP Scientific website**. Users obtain a starting point for primary drying duration and the maximum product temperature at the sublimation interface using pertinent information, such as shelf temperature and chamber pressure, from which an optimized freeze-drying cycle can be developed. The LMC is based on the steady-state heat and mass transfer model of primary drying developed by Dr. Michael Pikal with modifications by Dr. Robin Bogner and Royce Labriola at the University of Connecticut (USA).
The LyoModelling Calculator was developed for aqueous product in vials in direct contact with the shelves in a lyophilizer. Primary drying phase is a very...