Menu

Another CAR-T IPO

Cellectis goes public for a whopping $228 million—nearly double the value the company filed for in February.

Apr 6, 2015
Jef Akst

FLICKR, REYNERMEDIAThe Paris-based biotech Cellectis has joined a handful of other companies in going public with its chimeric antigen receptor (CAR) T-cell therapies, grossing more than $228 million in its initial public offering (IPO) on the Nasdaq last month (March 24). That value is $113 million more than the company initially filed for a month earlier, and makes it the second largest IPO in the CAR T space; Juno Therapeutics has retained the number-one spot with its $265 million IPO last December.

CAR T-cell therapies are a hot field, with dozens of organizations, including a handful of big pharma companies, working to develop T cells armed with receptors that bind particular cancer-associated antigens. In the last couple of years, hundreds of millions of dollars’ worth of deals have been struck, and dozens of clinical trials initiated. (Read more about the field in this month’s biobusiness article, “The CAR T-Cell Race.”)

Cellectis’s focus is on allogeneic T cells, or those taken from donated samples, in hopes of making an off-the-shelf therapy that can be more widely used than autologous cells. The company got a boost last year when it struck a deal with Pfizer for $80 million up front, plus up to $185 million per product and royalties. In its new IPO, Cellectis priced 5.5 million American shares at $41.50 each, with another 825,000 shares set away for the company’s underwriters. The money will go toward advancing four CAR-T candidates through Phase 1 trials, manufacturing the therapies, and work outside of oncology.

(Hat tip: Fierce Biotech)

September 2018

The Muscle Issue

The dynamic tissue reveals its secrets

Marketplace

Sponsored Product Updates

StemExpress LeukopakâNow Available in Frozen Format

StemExpress LeukopakâNow Available in Frozen Format

StemExpress, a Folsom, California based leading supplier of human biospecimens, announces the release of frozen Peripheral Blood Leukopaks. Leukopaks provide an enriched source of peripheral blood mononuclear cells (PBMCs) with low granulocyte and red blood cells that can be used in a variety of downstream cell-based applications.

New Antifade Mounting Media from Vector Laboratories Enhances Immunofluorescence Applications

New Antifade Mounting Media from Vector Laboratories Enhances Immunofluorescence Applications

Vector Laboratories, a leader in the development and manufacture of labeling and detection reagents for biomedical research, introduces VECTASHIELD® Vibrance™ – antifade mounting media that delivers significant improvements to the immunofluorescence workflow.

Best Practices for Sample Preparation and Lipid Extraction from Various Samples

Best Practices for Sample Preparation and Lipid Extraction from Various Samples

Download this white paper from Bertin Technologies to learn how to extract and analyze lipid samples from various models!

Bio-Rad Launches CHT Ceramic Hydroxyapatite XT Media and Nuvia HP-Q Resin for Process Protein Purification

Bio-Rad Launches CHT Ceramic Hydroxyapatite XT Media and Nuvia HP-Q Resin for Process Protein Purification

Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global leader of life science research and clinical diagnostic products, today announced the launch of two new chromatography media for process protein purification: CHT Ceramic Hydroxyapatite XT Media and Nuvia HP-Q Resin.