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Bats Identified as Source of Pig-Killing Coronavirus in China

The virus caused an outbreak that began in Guangdong Province and left nearly 25,000 piglets dead. 

Apr 4, 2018
Jim Daley

SUSAN ELLIS, WIKIMEDIA

Researchers have identified a coronavirus that killed nearly 25,000 piglets in China in 2016 and 2017. Zheng-Li Shi, a virologist at the Wuhan Institute of Virology in China, and her colleagues report today (April 4) in Nature that the virus, named swine acute diarrhea syndrome coronavirus (SADS-CoV), emerged from horseshoe bats (Rhinolophidae). The same species of bats were the source of severe acute respiratory syndrome (SARS), a related coronavirus that emerged in 2003. Unlike SARS, however, the new virus does not appear to infect humans.

The study should be “a warning of viral interspecies transmission between wildlife and domestic animals,” Shi tells Agence France-Presse (AFP). “It's normal that wildlife carry many viruses, bacteria, fungi, etc. As long as human society keeps away from wildlife, there is [a] very low chance of interspecies transmission.”

See “Bats a Major Global Reservoir of Coronaviruses

SADS-CoV was first identified in Guangdong Province in October 2016, where the virus had started killing piglets on a farm. At first, investigators believed the deaths were related to porcine epidemic diarrhea virus (PEDV), a common coronavirus in swine, after finding it in some of the animals, according to a National Institutes of Health report. But by January of 2017, they ruled out PEDV as the cause after it was no longer detected in dying piglets.

Shi and colleagues identified SADS-CoV in the small intestines of infected piglets. They sequenced its genome and discovered it was similar to another bat coronavirus identified in 2007. This prompted them to search for evidence of the new virus in bat specimens collected in Guangdong Province between 2013 and 2016. SADS-CoV was present in nearly 12 percent of the specimens.

The findings underscore “the importance of long-term surveillance for viruses in their natural reservoirs,” Shi tells AFP.

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