Menu

First RNAi Insecticide Approved

This month, the EPA registered four products that include RNA interference technology intended to control corn rootworms. 

Jun 27, 2017
Aggie Mika

WIKIMEDIA, TOM HLAVATY

   This month, the US Environmental Protection Agency (EPA) approved the first plant-incorporated protectant (PIP) of its kind based on RNA interference (RNAi) technology, engineered to target western corn rootworms (Diabrotica virgifera virgifera), The Atlantic reports. According to a statement issued this month (June 15) by the EPA, four SmartStax Pro seed products with the RNAi-based PIP have been registered thus far.

PIPs are pesticides that plants are able to produce themselves, thanks to modifications to the plants’ genes, according to the EPA. While some crops already contain RNAi-technology for the purposes of fending off certain viruses, among other uses, this is the first insecticide to take advantage of this technology.

See “Improving Crops with RNAi

RNAi is a ubiquitous process across plant and animal cells, during which short RNA molecules hinder gene expression by homing in on and subsequently cleaving their complementary messenger RNA transcripts.

See “RNA Interference Between Kingdoms

These SmartStax Pro corn seed products, The Atlantic reports, will incorporate DvSnf7 dsRNA. As prior research has demonstrated, this dsRNA, or double-stranded RNA, is specific to the western corn rootworm’s Snf7 gene. When a DvSnf7 dsRNA-containing plant is consumed by a corn rootworm, the dsRNA will initiate RNAi within the worm, leading to the suppression of this critical gene, and eventually, the rootworm’s demise.

The corn rootworm is “a devastating corn pest that has developed resistance to several other pesticides,” according to the EPA statement, that “can collectively cost corn growers in the U.S. over a billion dollars in terms of control costs and yield losses.”

According to The Atlantic, the EPA’s recent approval of the RNAi-based insecticide was “surprisingly low-key,” compared to the hullabaloo surrounding RNAi-based technology in the past. 

September 2018

The Muscle Issue

The dynamic tissue reveals its secrets

Marketplace

Sponsored Product Updates

StemExpress LeukopakâNow Available in Frozen Format

StemExpress LeukopakâNow Available in Frozen Format

StemExpress, a Folsom, California based leading supplier of human biospecimens, announces the release of frozen Peripheral Blood Leukopaks. Leukopaks provide an enriched source of peripheral blood mononuclear cells (PBMCs) with low granulocyte and red blood cells that can be used in a variety of downstream cell-based applications.

New Antifade Mounting Media from Vector Laboratories Enhances Immunofluorescence Applications

New Antifade Mounting Media from Vector Laboratories Enhances Immunofluorescence Applications

Vector Laboratories, a leader in the development and manufacture of labeling and detection reagents for biomedical research, introduces VECTASHIELD® Vibrance™ – antifade mounting media that delivers significant improvements to the immunofluorescence workflow.

Best Practices for Sample Preparation and Lipid Extraction from Various Samples

Best Practices for Sample Preparation and Lipid Extraction from Various Samples

Download this white paper from Bertin Technologies to learn how to extract and analyze lipid samples from various models!

Bio-Rad Launches CHT Ceramic Hydroxyapatite XT Media and Nuvia HP-Q Resin for Process Protein Purification

Bio-Rad Launches CHT Ceramic Hydroxyapatite XT Media and Nuvia HP-Q Resin for Process Protein Purification

Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global leader of life science research and clinical diagnostic products, today announced the launch of two new chromatography media for process protein purification: CHT Ceramic Hydroxyapatite XT Media and Nuvia HP-Q Resin.