Hubbub brews for HIV vax data

With just a week left until the full results of the Thai HIV vaccine trial are released, researchers are raising questions about whether the linkurl:preliminary data reported last month;http://www.the-scientist.com/blog/display/55995/ reveal but a small and misleading glimpse of the full study results. Meanwhile, a major AIDS healthcare provider this morning (October 12) linkurl:called for an independent evaluation of the data.;http://www.reuters.com/article/pressRelease/idUS75947+12-Oct-2009+BW

Jef Akst
Jef Akst

Jef Akst is managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.

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Oct 11, 2009
With just a week left until the full results of the Thai HIV vaccine trial are released, researchers are raising questions about whether the linkurl:preliminary data reported last month;http://www.the-scientist.com/blog/display/55995/ reveal but a small and misleading glimpse of the full study results. Meanwhile, a major AIDS healthcare provider this morning (October 12) linkurl:called for an independent evaluation of the data.;http://www.reuters.com/article/pressRelease/idUS75947+12-Oct-2009+BW20091012
Human Immunodeficiency Virus
Image: Wikimedia commons,
NIAID
Results of the $105 million HIV vaccination study, conducted in more than 16,000 Thai volunteers, showed that the vaccine decreased the risk of HIV infection by 31% compared to placebo. A second analysis not disclosed to the public, however, may negate these findings, linkurl:ScienceInsider reported;http://blogs.sciencemag.org/scienceinsider/2009/10/unrevealed-anal.html#more last week. At issue is the inclusion of those subjects who did not rigorously follow the protocols of the study. An analysis in which these individuals were excluded still showed a modest benefit from the vaccine, but it...
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