A genetic variant on the X chromosome may explain why some HIV-infected women are slower to develop full-blown AIDS than men. Although several human genetic variants have been implicated in the control and spread of HIV within a host, this is the first time that a sex chromosome has been found to harbor a suspect stretch of genome related to the disease.
"I think it's a fascinating piece of work," linkurl:Sunil Ahuja,;http://class.ysu.edu/~polisci/ahuja/index.html an infectious disease geneticist at the University of Texas Health Science Center in San Antonio, told __The Scientist__. "It allows us to begin to probe some of those rather tantalizing reports that [HIV-infected] women generally do better than men," added Ahuja, who was not involved with the study. German researchers identified a single-nucleotide polymorphism (SNP) located on the X chromosome of...
Image: C. Goldsmith, courtesy
of the Centers for Disease
Control and Prevention
Interested in reading more?
Become a Member of
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!