Old ovaries, new eggs

Are female mammals born with all the eggs they'll ever have, or can they produce new eggs into adulthood? The question has been vociferously debated, but now, a study published online in Nature Cell Biology today (April 12) reports that at least in mice, adult female ovaries have a store of stem cells that have the potential to generate new eggs. Human oocyte Image: Wikimedia CommonsThe study "is a huge step in quelling this debate," Jonathan Tilly, a reproductive biologist at Harvard Medical

Tia Ghose
Apr 11, 2009
Are female mammals born with all the eggs they'll ever have, or can they produce new eggs into adulthood? The question has been vociferously debated, but now, a study published online in Nature Cell Biology today (April 12) reports that at least in mice, adult female ovaries have a store of stem cells that have the potential to generate new eggs.
Human oocyte

Image: Wikimedia Commons
The study "is a huge step in quelling this debate," Jonathan Tilly, a reproductive biologist at Harvard Medical School, told The Scientist. "You're starting to look at a body of evidence that you simply can't refute anymore." The idea that mammals stop forming new eggs at birth has held sway since the 1950's, but in 2004, Tilly and his colleagues published a paper in Nature claiming they had found germ line stem cells--those responsible for forming new sex cells like sperm and...