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Top 7 in cell biology

1. Parasite's unusual metabolism __Plasmodium falciparum__ may have evolved a unique, non-cyclic version of the textbook energy-producing process in cells known as the Krebs cycle -- presumably as an adaptation to living inside human blood cells -- a finding that could lead to new Malaria drug targets. K.L. Olszewski et al., linkurl:Nature,;http://www.ncbi.nlm.nih.gov/sites/entrez/20686576?dopt=Abstract&holding=f1000,f1000m,isrctn 2010 Aug 2 466:774-8. linkurl:Eval by;http://f1000biology.com/a

Cristina Luiggi
1. Parasite's unusual metabolism __Plasmodium falciparum__ may have evolved a unique, non-cyclic version of the textbook energy-producing process in cells known as the Krebs cycle -- presumably as an adaptation to living inside human blood cells -- a finding that could lead to new Malaria drug targets. K.L. Olszewski et al., linkurl:Nature,;http://www.ncbi.nlm.nih.gov/sites/entrez/20686576?dopt=Abstract&holding=f1000,f1000m,isrctn 2010 Aug 2 466:774-8. linkurl:Eval by;http://f1000biology.com/article/tp16n4ws0xhmqc8/id/4568990 Paul Roepe, Georgetown Univ.; Robert Abraham, Pfizer; Frank Seeber, Humboldt-Universit?t zu Berlin; ID: 4568990
Microtubule segment
Image:Wikimedia Commons
2. Overlapping microtubules Researchers identified two proteins essential for monitoring the extent to which microtubules, spun from the poles of dividing cells, overlap when they meet in a region known as the midzone in vitro -- furthering the understanding of how microtubules orchestrate the partitioning of a cell's contents into two daughter cells. P. Bieling et al., linkurl:Cell,;http://www.ncbi.nlm.nih.gov/sites/entrez/20691901?dopt=Abstract&holding=f1000,f1000m,isrctn 2010 Aug 6 142:420-32. linkurl:Eval by;http://f1000biology.com/article/k2vzhlr13gl66d8/id/4795958 Linda Wordeman, Univ. Washington School of Medicine; Sidney Shaw, Indiana...
3. More on cell divisionF. Wang, et al., linkurl:Science,;http://www.ncbi.nlm.nih.gov/sites/entrez/20705812?dopt=Abstract&holding=f1000,f1000m,isrctn 2010 Aug 12 doi: 10.1126/science.1189435. linkurl:Eval by;http://f1000biology.com/article/377m7xt67t8w91t/id/4884975 Kyung Lee, NIH; Rene Medema, Univ. Medical Center Utrecht, Netherlands; Stephanie Ems-McClung and Claire Walczak, Indiana Univ; ID: 48849754. Stiffening embryosJ. Zhou et al., linkurl:Development,;http://www.ncbi.nlm.nih.gov/sites/entrez/20630946?dopt=Abstract&holding=f1000,f1000m,isrctnlink 2010 Aug 137:2785-94. linkurl:Eval by;http://f1000biology.com/article/9630s7k8g6tmq7c/id/4234956 John Wallingford, Univ. of Texas at Austin; Ronen Zaidel-Bar, National Univ. of Singapore; Michel Labouesse, Centre National de la Reserche Scientifique, France; ID: 42349565. Rewiring heart cellsM. Ieda et al., linkurl:Cell,;http://www.ncbi.nlm.nih.gov/sites/entrez/20691899?dopt=Abstract&holding=f1000,f1000m,isrctn 2010 Aug 6 142:375-86. linkurl:Eval by;http://f1000biology.com/article/6lykbdjymvhkhxf/id/4873956 Enrique Lara-Pezzi and Nadia Rosenthal, European Molecular Biology Laboratory (EMBL); ID: 48739566. A melange of infectionsM. Desnos-Ollivier et al., linkurl:mBio,;http://www.ncbi.nlm.nih.gov/sites/entrez/20689742?dopt=Abstract&holding=f1000,f1000m,isrctn 2010 Aug 1(1) doi:10.1128/mBio.00091-10. linkurl:Eval by;http://f1000biology.com/article/vm48v7rzx5tcwcf/id/4799956 Arturo Casadevall, Albert Einstein College of Medicine; Wenjun Li and Joe Heitman, Duke Univ. Medical Center; ID: 47999567. Methylating enzymeC.E. Schaner Tooley et al., linkurl:Nature,;http://www.ncbi.nlm.nih.gov/sites/entrez/20668449?dopt=Abstract&holding=f1000,f1000m,isrctn 2010 Aug 26 466:1125-28. linkurl:Eval by;http://f1000biology.com/article/3x00hhlpk7njxyx/id/4489956 Paul Clarke, University of Dundee, UK; Philip Cole, Johns Hopkins University School of Medicine; ID: 4489956



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