Trial registries not working

Clinical trial registries -- set up in the last few years to ensure trial data see the light of day -- are a long ways from correcting the problem, says linkurl:a report;http://jama.ama-assn.org/cgi/content/full/302/9/977?home to be published in the Journal of the American Medical Association (JAMA) tomorrow (September 2). Image: Wikimedia Commons "This sort of evidence is disappointing, I think," said linkurl:Ian Roberts,;http://www.lshtm.ac.uk/people/roberts.ian a professor of epidemiology an

Alla Katsnelson
Aug 31, 2009
Clinical trial registries -- set up in the last few years to ensure trial data see the light of day -- are a long ways from correcting the problem, says linkurl:a report;http://jama.ama-assn.org/cgi/content/full/302/9/977?home to be published in the Journal of the American Medical Association (JAMA) tomorrow (September 2).
Image: Wikimedia Commons
"This sort of evidence is disappointing, I think," said linkurl:Ian Roberts,;http://www.lshtm.ac.uk/people/roberts.ian a professor of epidemiology and public health at the London School of Hygiene and Tropical Medicine who was not involved in the study. "It seems to me that there is a lack of implementation and enforcement" in registering trials in such databases. Clinical trial registries were one solution proposed to fight what's known as publication bias, or when trial sponsors fail to publish negative data. For instance, sometimes an original outcome measure will fail to show an effect of a treatment, so the trial sponsors publish the...
British Medical JournalThe LancetJAMAThe ScientistThe Lancet



Interested in reading more?

Become a Member of

Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?