Tumors spur depression

Tumors can cause classic symptoms of depression in rats, according to linkurl:a new study published online in PNAS;http://www.pnas.org/content/early/2009/05/15/0811949106.abstract this week. Image: linkurl:Understanding Animal Research;http://www.understandinganimalresearch.org.uk/ "What's really cool about this paper is that it shows without a doubt that there are depressive-like behaviors induced in these rats before these rats become [sick]," said linkurl:Keith Kelley,;http://www.iib.uiuc.e

Jef Akst
Jef Akst

Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf...

View full profile.


Learn about our editorial policies.

May 17, 2009
Tumors can cause classic symptoms of depression in rats, according to linkurl:a new study published online in PNAS;http://www.pnas.org/content/early/2009/05/15/0811949106.abstract this week.
Image: linkurl:Understanding Animal Research;http://www.understandinganimalresearch.org.uk/
"What's really cool about this paper is that it shows without a doubt that there are depressive-like behaviors induced in these rats before these rats become [sick]," said linkurl:Keith Kelley,;http://www.iib.uiuc.edu/faculty/faculty/k_kelley.cfm an immunophysiologist at the University of Illinois at Urbana-Champaign, who was not involved in the research. Researchers have long known that individuals suffering from chronic illness are at a greater risk of depression, but whether it was a direct cause of the illness or a psychological reaction to being sick was unclear. "By using this animal model of cancer we were able to isolate just the physiological effects of the tumors from the psychological effects that you get in human studies," said linkurl:Leah Pyter,;http://home.uchicago.edu/%7Epyter/ a behavioral neuroscientist at the University of Chicago, who led the...




Interested in reading more?

Become a Member of

Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?