World’s Largest Cell and Gene Therapy Plant Opens

Lonza will employ more than 200 full-time staff to work at the Texas-based facility, the company says.

Apr 11, 2018
Catherine Offord

ISTOCK, D3DAMONSwiss chemicals and biotech company Lonza officially opened its new cell and gene therapy manufacturing plant in Pearland, near Houston, Texas, yesterday (April 10). The facility’s 300,000 square feet make it the world’s largest manufacturing plant devoted to making these types of materials, according to a statement.

“This facility has the potential to produce treatment for thousands of patients suffering from rare genetic disorders or life-threatening diseases, under one roof,” Andreas Weiler, business unit head of technologies at Lonza, says in the statement. “It will set a new standard in biopharmaceutical manufacturing.”

See “World's First Commercial iPSC Cell Plant Opens in Japan

One of the key goals of the plant, officially named the Lonza Houston Center of Excellence, will be to engineer viruses as gene-therapy vectors—shortages of which have created bottlenecks across the industry in recent years.

According to Lonza, the plant is already manufacturing products for some customers. By the end of 2018, the company plans to have recruited a full-time staff of more than 200 people, including scientists and engineers. “Cell and gene therapies will become mainstream,” Weiler tells Reuters. “We already see this from the investments of our large pharma and biotech customers.”

Although the venture is an expensive one, the decision to make the ingredients for many therapies rather than one or two complete products may help Lonza distribute its risk in a still relatively young industry, Martin Lehmann, whose Zurich-based fund 3V Invest Swiss Small & Mid Cap owns shares in Lonza, tells Reuters.

For investors, companies like Lonza “aren’t an all-or-nothing proposition, where a single therapy’s failure can lead to a 60 or 70 drop in a company’s stock inside of a day,” he says.