Menu

Horizon Discovery introduces Myeloid DNA Reference Standard to support genetic testing of leukemia

Horizon Discovery Group plc, a global leader in gene editing and gene modulation technologies, today announced the launch of its Myeloid DNA Reference Standard. The first-to-market large cell-line derived myeloid cancer reference standard designed enables faster, more reliable and more cost-effective assay validation, to support the market in bringing routine testing into practice.

Sep 24, 2018
Horizon Discovery

Horizon Discovery Group plc (LSE: HZD) (“Horizon” or “the Company”), a global leader in gene editing and gene modulation technologies, today announced the launch of its Myeloid DNA Reference Standard. The first-to-market large cell-line derived myeloid cancer reference standard designed enables faster, more reliable and more cost-effective assay validation, to support the market in bringing routine testing into practice.


The latest addition to the Company’s portfolio of over 100 Reference Standards, the Myeloid DNA Reference Standard has been developed using Horizon’s specialist gene editing technology, to deliver a cell line-derived reference standard containing 22 mutations across 19 genes that are commonly associated with myeloid cancer. This provides genetic testing laboratories and assay developers with a tool to effectively validate and optimize myeloid genetic tests with DNA of known genotype which closely mimics the genomic DNA format and mutations present in real patient samples. The Myeloid DNA Reference Standard contains variants in more genes than most clinical material, enabling quality assurance goals to be reached faster.


Blood cancers have seen increased biomarker identification and associated targeted drug development in recent years, resulting in an increase in genetic testing of myeloid cancer. There are now multiple pre-designed, multi-gene next generation sequencing (NGS) assays on the market, in addition to custom-designed myeloid gene panels. Myeloid cancer has more associated actionable gene targets that can direct clinical treatment options than are available for solid tumors, meaning that high quality, accurate genetic diagnosis is vital to guide treatment of cancer patients. The new Myeloid DNA Reference Standard fulfils the need for clinical testing labs and assay developers to access well-characterized, multigene multiplexed reference standards.


Terry Pizzie, Chief Executive Officer, Horizon Discovery Group, commented:This is an exciting new launch for Horizon as it is the largest cell-line derived reference standard hitting the market that is focused exclusively on myeloid cancer. Horizon has successfully developed an extensive range of genetically defined, human genomic reference standards already, and the Myeloid DNA Reference Standard further demonstrates our commitment to providing the right tools our customers need to tackle the challenges of oncology genetic testing.”

June 2019

Living with Bacteria

Can pathogens be converted to commensals?

Marketplace

Sponsored Product Updates

Sartorius debuts the Intellicyt iQue3 at CYTO® 2019
Sartorius debuts the Intellicyt iQue3 at CYTO® 2019
Sartorius will be showcasing the latest addition to its cellular analysis portfolio on booth #103 at this year’s CYTO® conference and exhibition, with the launch of the Intellicyt iQue3. 
Expedeon AG introduces Lightning-Link Metal Labeling Kits to support single cell analysis
Expedeon AG introduces Lightning-Link Metal Labeling Kits to support single cell analysis
Novel antibody labeling immunoassay technology for multiplex immune profiling addresses one of the fastest growing, billion-dollar life science market sectors
Best Practices: Calculating Cell Confluency
Best Practices: Calculating Cell Confluency
In this white paper, learn how to use a cell imager system to directly and accurately capture and calculate cell confluency!
LabTwin's AI-powered Digital Assistant Now Talks Back and Connects Data Sources in the Lab with New Open API
LabTwin's AI-powered Digital Assistant Now Talks Back and Connects Data Sources in the Lab with New Open API
LabTwin GmbH, the world's first voice and AI-powered digital lab assistant, today announced its new open API that will connect scientists with data sources both inside and outside of the lab.