Courtesy of Dynal Biotech
Oslo-based Dynal Biotech
Dynal's newest kit, the Mouse CD3/CD28 T-cell Expander, eliminates much of the tedium from the task of T-cell expansion. Released to complement Dynal's human T-cell expander, as well as its recently launched kit for mouse B-cell negative isolation, the kit bridges the gap between human research and animal models.
Conventional T-cell expansion methods require that researchers maintain a separate line of antigen-presenting cells (APCs). "You have to use live cells, and keep them in culture, and feed them. It's much more tedious," says Dynal product manager Erik Ruud. The cell-sized Dynabeads (4.5 μm in diameter) are coated with anti-CD3 and anti-CD28 monoclonal antibodies to mimic the effects...