linkurl:1. SWEET proteins found;http://www.f1000biology.com/article/w7k0gdj9cm62gtt/id/6785956 A new class of proteins, dubbed SWEETs, function as glucose transporters, shuttling sugar molecules out of plant, worm and human cells. In some plants, SWEET proteins are co-opted by bacterial pathogens to deliver nutrition to the invaders.L.Q. Chen et al., linkurl:"Sugar transporters for intercellular exchange and nutrition of pathogens,";http://www.ncbi.nlm.nih.gov/sites/entrez/21107422?dopt=Abstract&holding=f1000%2Cf1000m __Nature__, 468:527-32, 2010. Evaluations by Julian Schroeder, UCSD; Akiko Sugio and Saskia Hogenhout, The John Innes Centre, UK; John Patrick, Univ Newcastle, Australia; David Alpers, Wash U Sch of Med; Bruno Stieger, Univ Hosp Zurich; Tapio Palva, Univ Helsinki; H Ekkehard Neuhaus, Univ Kaiserslautern, Germany. linkurl:Free F1000 Evaluation;http://www.f1000biology.com/article/w7k0gdj9cm62gtt/id/6785956 linkurl:2. Codons boost protein expression;http://www.f1000biology.com/article/8t1j76m6ygprt0b/id/1160043 A library of more than 150 synthetic green fluorescent protein genes, inserted into E. coli DNA, showed that changing synonymous codons -- different nucleotide triplets that encode the same amino acid -- can alter protein expression up to 250-fold, likely a result of...
G. Kudla et al., linkurl:"Coding-sequence determinants of gene expression in Escherichia coli,";http://www.ncbi.nlm.nih.gov/sites/entrez/19359587?dopt=Abstract&holding=f1000%2Cf1000m __Science__, 324:255-58, 2009. Evaluations by Jonathan R Warner, Albert Einstein Coll of Med; Panayiotis Benos, Univ Pitt; Daniel Dykhuizen, Stony Brook; Jurg Bahler, UCL; Neeraj Dhar and John McKinney, EPFL, Switzerland; Audrey Gasch, Univ Wisc-Madison. linkurl:Free F1000 Evaluation;http://www.f1000biology.com/article/8t1j76m6ygprt0b/id/1160043
Astrocyte with focal adhesion kinases
tagged green
Image: Neurorocker at en.wikipedia
linkurl:3. Focus on focal adhesions;http://www.f1000biology.com/article/nfjlg58s3qm3l70/id/6623956 P. Kanchanawong et al., linkurl:"Nanoscale architecture of integrin-based cell adhesions,";http://www.ncbi.nlm.nih.gov/sites/entrez/21107430?dopt=Abstract&holding=f1000%2Cf1000m __Nature__, 468:580-84, 2010. Evaluations by Martin Humphries, Univ Manchester; Herbert Schiller and Reinhard Fassler, Max Planck Gesellschaft, Germany; Ronen Zaidel-Bar, Nat Univ Singapore; John Couchman, Univ Copenhagen. linkurl:Free F1000 Evaluation;http://www.f1000biology.com/article/nfjlg58s3qm3l70/id/6623956 linkurl:4. The degradation trick;http://www.f1000biology.com/article/byqx3xlcj6b6059/id/5674957 F. Zhang et al., linkurl:"Differential arginylation of actin isoforms is regulated by coding sequence-dependent degradation,";http://www.ncbi.nlm.nih.gov/sites/entrez/20847274?dopt=Abstract&holding=f1000%2Cf1000m __Science__, 329:1534-37, 2010. Evaluations by Sarah M P Jacobo and Andrius Kazlauskas, Harvard Med Sch; Jike Cui and Dennis Wall, Harvard Med Sch; Irina Kaverina, Vanderbilt Univ Med Cntr; Zhihua Li and Edward M Marcotte, Univ Texas. linkurl:Free F1000 Evaluation;http://www.f1000biology.com/article/byqx3xlcj6b6059/id/5674957 linkurl:5. Fat rat daddies have diabetic daughters;http://www.the-scientist.com/news/display/57757/ S.F. Ng et al., linkurl:"Chronic high-fat diet in fathers programs beta-cell dysfunction in female rat offspring,";http://www.ncbi.nlm.nih.gov/sites/entrez/20962845?dopt=Abstract&holding=f1000%2Cf1000m __Nature__, 467:963-6, 2010. Evaluations by Russell Bonduriansky, Univ New South Wales, Australia; Enrico Avvedimento, Univ Federico II, Italy; Qingchun Tong and Perry Bickel, Univ Texas; Atsushi Iriki, RIKEN Brain Sci Inst, Japan; Mehboob Hussain, Johns Hopkins Univ; William H Colledge, Univ Cambridge. linkurl:Free F1000 Evaluation;http://f1000.com/5758956?key=5qy0jc0fyrrpcgf linkurl:6. Shaping the ER;http://www.f1000biology.com/article/m48j8v427ksk2n7/id/6989956 Y. Shibata et al., linkurl:"Mechanisms determining the morphology of the peripheral ER,";http://www.ncbi.nlm.nih.gov/sites/entrez/21111237?dopt=Abstract&holding=f1000%2Cf1000m __Cell__, 143:774-88, 2010. Evaluations by Charles Barlowe, Dartmouth Med Sch; Matthias Seedorf, Univ Heidelberg, Germany; Sascha Martens, Univ Vienna. linkurl:Free F1000 Evaluation;http://www.f1000biology.com/article/m48j8v427ksk2n7/id/6989956 linkurl:7. The genome shuffle;http://www.the-scientist.com/news/display/57907/ P.J. Stephens et al., linkurl:"Massive genomic rearrangement acquired in a single catastrophic event during cancer development,";http://www.ncbi.nlm.nih.gov/sites/entrez/21215367?dopt=Abstract&holding=f1000%2Cf1000m __Cell__, 144:27-40, 2011. Evaluations by Jordi Camps and Thomas Ried, NCI/NIH; Yamini Dalal, NCI/NIH; Giovanni Neri, Univ Cattolica del S Cuore, Italy; Robert Booth, Virobay Inc; Yan Xu and Makoto Komiyama, Univ Tokyo. linkurl:Free F1000 Evaluation;http://www.f1000biology.com/article/g79vstgp2slq12q/id/7848958




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