linkurl:1. Clock calibrated by temp;
Mouse cingulated cortex neurons
Image: Wikimedia commons, Shushruth
The suprachiasmatic nucleus, a tiny area in the middle of the brain responsible for controlling circadian rhythms, uses small fluctuations in the body temperatures of mammals to coordinate the daily rhythms of tissues throughout the body. E.D. Buhr ED, et al., "Temperature as a universal resetting cue for mammalian circadian oscillators," linkurl:Science,; 330:79-85, 2010. Evaluated by Jean Clairambault, INRIA; Patrick Fuller and Clifford Saper, Beth Israel Deaconess Med Cen, Harvard Med School; Ralph Mistlberger, Simon Fraser Univ; Stacey Harmer, UC Davis. linkurl:Free F1000 Evaluation; linkurl:2. Prozac transforms neurons; In Prozac-treated mice, increased levels of the microRNA miR-16 reduces the expression of the serotonin transporter (SERT) in serotonergic neurons, while decreased miR-16 levels in noradrenergic neurons turns on the expression of serotonergic functions, suggesting that antidepressants can modify the neuronal phenotype.A. Baudry, et al. "miR-16...
linkurl:3. Flies have "eyes" on their backs; DrosophilaY. Xiang, et al., "Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall," linkurl:Nature,; 468:921-6, 2010. Evaluated by Steven Reppert, Univ of Mass Med School; Gray Lyons and Chay T Kuo, Duke Univ Med Cen. linkurl:Free F1000 Evaluation; linkurl:4. Dopamine does and doesn't help learning; S.B. Flagel, et al., "A selective role for dopamine in stimulus-reward learning," linkurl:Nature,; 469:53-7, 2010. Evaluated by Björn Brembs Freie Univ Berlin; Xiaoxi Zhuang, Univ of Chicago. linkurl:Free F1000 Evaluation; linkurl:5. Shuffling neurons aids spatial memory; D. Dupret, et al., "The reorganization and reactivation of hippocampal maps predict spatial memory performance," linkurl:Nat Neurosci,; 13:995-1002, 2010. Evaluated by Lisa Giocomo and Edvard I Moser, Norwegian Univ of Sci and Tech; Howard Eichenbaum, Boston Univ. linkurl:Free F1000 Evaluation; linkurl:6. Fear fighting neurons; W. Haubensak, et al., "Genetic dissection of an amygdala microcircuit that gates conditioned fear," linkurl:Nature,; 468:270-6, 2010. Evaluated by Kerry Ressler, Yerkes National Primate Res Cen; Matt E Carter and Luis de Lecea, Stanford Univ. linkurl:Free F1000 Evaluation; linkurl:7. Lungs can taste; A.S. Shah, et al., "Motile cilia of human airway epithelia are chemosensory," linkurl:Science,; 325:1131-4, 2009. Evaluated by Stephen Roper, Univ of Miami School of Med; Arturo Alvarez-Buylla, Univ of Calif; Sue Kinnamon, Colorado State Univ. linkurl:Free F1000 Evaluation; The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Neuroscience, as calculated on January 20, 2011. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit linkurl:;

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