Researchers have identified a distinct group of early-stage linkurl:neural stem cells,; called neural rosette cells, that can form more types of neural cells than typical neural stem cells, reports a study published today (January 14) in linkurl:__Genes & Development__.; As neural stem cells develop from embryonic stem cells, they form a radial pattern of epithelial cells, called rosettes. Scientists had seen the morphology before, but "nobody understood rosette cells," linkurl:Lorenz Studer; at Memorial Sloan-Kettering Cancer Center, the lead investigator on the study, told __The Scientist__. Studer and his colleagues isolated neural rosette cells and profiled them genetically, finding an expression pattern distinct from linkurl:neural stem cells.; But the most exciting quality of rosette cells is that it appears they can develop into any type of neural cell, representing a population that behaves more like linkurl:true stem cells.; Whereas neural stem cells in culture typically only differentiate into GABA-ergic or glutamatergic...

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