Preclinical Research

Preclinical is the step between discovery research and clinical trials. Because clinical trials are so expensive, preclinical research is an important step in selecting only those drug candidates that have the greatest chance of success. This work involves testing drug candidates in cell lines and in animal models to demonstrate efficacy and safety.

Toby Freedman
May 31, 2008

Personality test
• Do you like working on the practical side of drug discovery? This area requires creative-minded scientists capable of innovative thought, yet capable of working in a more directed and collaborative environment.
• Are you a meticulous record keeper? Your results could become part of regulatory filings.
• Are you able to speak the language of in vitro and in vivo scientists, and clinicians? All are important in this role.

Pros
• Still scientific.
Even though it's a bit more applied, the science is still the biggest part of the job, and you are relied on as the expert in your area.
• More than discovery.
As a preclinical scientist, you will be more tuned into what's happening in clinical, manufacturing, and regulatory areas - exposure that discovery scientists rarely have.
• Focus on best ideas.
You will...