Supplement: Drano for the Arteries

Drano for the Arteries By Jack Lucentini ARTICLE EXTRAS Innovative Technology Technology Roundup Greater Philadelphia Innovation --> Bristol Myers-Squibb Rutgers-Camden Institute Neuronetics Temple University Absorption Systems Tengion Kimmel Cancer Center Orphagenix BioNanomatrix If it works as hoped, it could be the next blockbuster drug: one that shrinks artery-clogging atherosclerotic plaque, the leading cause of the

Jack Lucentini
Jan 1, 2008
Drano for the Arteries
By Jack Lucentini

If it works as hoped, it could be the next blockbuster drug: one that shrinks artery-clogging atherosclerotic plaque, the leading cause of the heart attacks that kill some half a million people annually in the United States.

Daniel Rader, a cardiologist at the University of Pennsylvania School of Medicine, is studying several compounds that researchers say might be successful. Rader is a "key scientist" in this field, and the "prototype of a translational researcher - he goes between patients and the lab," says Glenn Gaulton, executive vice dean and chief scientific officer at Penn. While there are medicines to prevent buildup of cholesterol, a key component of plaque, there aren't any to clear it from the bloodstream, he...

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