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Systems biology at biotechnology and pharmaceutical

Systems biology at biotechnology and pharmaceutical companies In an effort to restock the dwindling pipeline of new treatments, systems biology is increasingly becoming a part of drug discovery efforts. Company Approach Location Bioseek Screen novel compounds with combinations of human primary cells to measure activity and understand their mechanism of action Burlingame, California Gene Network Sciences Use models to improv

Brendan Borrell

Systems biology at biotechnology and pharmaceutical companies

In an effort to restock the dwindling pipeline of new treatments, systems biology is increasingly becoming a part of drug discovery efforts.

Bioseek

Screen novel compounds with combinations of human primary cells to measure activity and understand their mechanism of action

Burlingame, California

Gene Network Sciences

Use models to improve quality of pre-clinical compounds and guide the design of clinical trials.? Evaluate cardiovascular safety with Visual Heart.?

Ithaca, New York

Genstruct

Apply causal-inference models to identify biomarkers for drug toxicity, drug resistance, and cardiovascular drug mechanisms.

Cambridge, Massachusetts

Rosetta Inpharmatics
(subsidiary of Merck)

Identify targets in gene networks regulating obesity, diabetes, and other phenotypic traits, using microarray techniques.

Seattle, Washington

Optimata

Use a human physiological model designed for understanding disease dynamics and optimizing drug and treatment schedules

Ramat Gan, Israel

Entelos

Use virtual patients, recently modeling skin sensitivity for the...

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